A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier. The intestinal epithelium, a...

UC Riverside-led study is the first to show how tofacitinib rescues gut barrier function from overactive immune cells

UC Riverside mouse study will identify mechanisms the gene PTPN2 uses to affect gut cells

UC Riverside-led study is the first to show how tofacitinib affects epithelial cells lining the gut

UC Riverside-led study tested the effects of microgravity on intestinal epithelial cells