UC Riverside-led study sheds light on how IBD can develop

Inflammatory bowel disease, or IBD, describes Crohn’s disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune disorder — a condition in which the body’s immune system attacks healthy tissues. Its symptoms include...

By Iqbal Pittalwala | | Health

A more targeted therapy to treat inflammatory bowel disease

UC Riverside mouse study focuses on the receptor TNFR1

By Iqbal Pittalwala | | Health

Novel mechanism links genetic defect in IBD patients to gut leakiness

UC Riverside-led study in mice and human tissue is the first to show how a disease mutation weakens barrier properties of epithelial cells lining the gut

By Iqbal Pittalwala | | Health

Drug found to correct gene defect that causes immune-driven gut leakiness

UC Riverside-led study is the first to show how tofacitinib rescues gut barrier function from overactive immune cells

By Iqbal Pittalwala | | Health

Understanding a gene’s role in inflammatory bowel disease

UC Riverside mouse study will identify mechanisms the gene PTPN2 uses to affect gut cells

By Iqbal Pittalwala | | Health

Drug decreases gut leakiness associated with ulcerative colitis

UC Riverside-led study is the first to show how tofacitinib affects epithelial cells lining the gut

By Iqbal Pittalwala | | Health

Space travel can make the gut leaky

UC Riverside-led study tested the effects of microgravity on intestinal epithelial cells

By Iqbal Pittalwala | | Health